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2-NICOTINAMIDOETHYL NITRATE
Descriptors Found:
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DeCS
Descriptor
English
:
Nicorandil
Descriptor
Spanish
:
Nicorandil
Descriptor
Portuguese
:
Nicorandil
Synonyms
English
:
2-Nicotinamidoethyl Nitrate
Tree Number:
D02.583.575
D03.066.515.530.498
D03.383.725.547.530.498
Definition
English
:
A derivative of the
NIACINAMIDE
that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of
arterioles
and large coronary
arteries
. Its nitrate-like properties produce venous
vasodilation
through stimulation of
guanylate cyclase.
Pharmacological Action:
Anti-Arrhythmia Agents
Antihypertensive Agents
Vasodilator Agents
Vitamin B Complex
History Note
English
:
99; use NICORANDIL (NM) 1978-98
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
33810
Unique Identifier:
D020108
Occurrence in VHL
:
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